Naming, Addressing and Control in Cell Biology

Topics

• Modeling dynamics with stoichiometry matrices
• Modules in biosynthesis: carriers, precursors and pathways
• Control: Fastest: allosteric, Fast: translation, Slow: transcription, example lac operon
• Naming and addressing via molecular recognition, example: lambda phage repressor

Slides

• Modular structures in cell biology
• Control in proteins

Reading

• A Genetic Switch, Third Edition: Phage Lambda Revisited , Ptashne
• An Introduction to Systems Biology: Design Principles of Biological Circuits, Alon, Uri
• Highly optimised global organisation of metabolic networks, R. Tanaka, M. Csete and J. Doyle
• Quantitative evaluation of scale-rich metabolic networks, Tanaka, Doyle